Furthermore, the sympathetic nervous system may play a regulatory role in secondary lymphoid organs as it has been shown that selective sympathectomy in secondary lympoid organs exacerbates experimental arthritis.
Morphological and functional studies revealed a complex system of primary sensory neurons which parallels the autonomic nervous system not only in its extent, but probably also in its significance. Neuropeptides released from activated nociceptive afferent nerves play a pivotal role in inflammatory reactions and pain, significantly modulate cardiac, vascular, respiratory, gastrointestinal and immune functions and influence the protective, restorative and trophic functions of somatic and visceral tissues.
Publication Date: 2009-01-01
Publisher: Elsevier Science & Technol