During surgery, melatonin circadian rhythm and serotonin levels did not change, but melatonin increased only at night and serotonin decreased after surgery. These findings suggested that some stress stimuli are conducted via cervical sympathetic nerves to the hypothalamus, which is reduced by SGB, and to the pineal gland at night, which causes increased melatonin and decreased serotonin levels.
Authors: Iwama, Hiroshi; Son, Syoraku; Watanabe, Kazuhiro
Source: The Pain Clinic, Volume 13, Number 3, 2001 , pp. 233-244(12)
Publisher: Maney Publishing