A number of the experimental and clinical approaches to protection against noise-induced hearing loss involve mechanisms related to CBF and the oxygenation of the cochlea. These are such diverse procedures as sympathectomy, hyperbaric oxygen treatment and carbogen respiration. It is not within the scope of this review to address the literature concerning these and other approaches comprehensively, but is useful to consider a few examples and their relative success. Strategies in relation to ROS are covered in the next section.
Year : 1999 | Volume : 2 | Issue : 5 | Page : 17-31 | |
Sound-induced cochlear ischemia/hypoxia as a mechanism of hearing loss | |
Nuttall Alfred L Department of Otolaryngology, NRC04, Oregon Health Sciences University, Portland, Oregon, USA and Kresge Hearing Research Institute, University of Michigan, Ann Arbor, MI 97201-3098, USA, |