"Sympathectomy is a technique about which we have limited knowledge, applied to disorders about which we have little understanding." Associate Professor Robert Boas, Faculty of Pain Medicine of the Australasian College of Anaesthetists and the Royal College of Anaesthetists, The Journal of Pain, Vol 1, No 4 (Winter), 2000: pp 258-260
Sunday, June 30, 2013
Several reports have dealt with the alteration of antibody responses of spleen and lymph nodes following sympathectomy
http://www.ncbi.nlm.nih.gov/pubmed/8528891
Impairment of heart action following various methods of surgical denervation
A considerable variation in the distribution of fibres from the left sympathetic trunk to the right heart and from the right sympathetic trunk to the left side of the heart has also been shown (Randall et al., 1968a). However, the normal pattern is that large sympathetic nerves reach the base of the heart anteriorly and descend on either side of the main pulmonary artery. Nerves descending on the right of the pulmonary artery go to the atria and right ventricle.
Interruption of afferent and efferent innervation of the heart also produces a response from circulatory and renal systems.
Surgical cardiac denervation was carried out in 25 greyhounds and their responses to exercise, propranolol, and atropine were observed between one and three months afterwards. Our experiments confirm that a denervated heart shows delayed and diminished response to exercise and no response to atropine and propranolol.
Interruption of afferent and efferent innervation of the heart also produces a response from circulatory and renal systems.
Surgical cardiac denervation was carried out in 25 greyhounds and their responses to exercise, propranolol, and atropine were observed between one and three months afterwards. Our experiments confirm that a denervated heart shows delayed and diminished response to exercise and no response to atropine and propranolol.
Impairment of heart action following various methods of surgical denervation
T. J. OTTO' and P. C. CHEAH
The Nuffield Unit of Clinical Physiology, Department of Surgery, Royal Postgraduate Medical School, Ducane Road, London, W.12
Thorax(1970),25,199.
T. J. OTTO' and P. C. CHEAH
The Nuffield Unit of Clinical Physiology, Department of Surgery, Royal Postgraduate Medical School, Ducane Road, London, W.12
Thorax(1970),25,199.
Sympathectomy significantly alters vascular responses
Vascular responses to warming were studied in hemiplegic patients and after sympathectomy, using venous occlusion plethysmography of foot and leg. Comparisons were made with corresponding age groups. The pattern of response was essentially unchanged in hemiplegic patients, but was altered substantially where sympathetic pathways had been interrupted.
Vasomotor Responses in the Extremities of Subjects with Various Neurologic Lesions
I. Reflex Responses to Warming
- WALTER REDISCH, M.D.;
- FRANCISCO T. TANGCO, M.D.;
- LOTHAR WERTHEIMER, M.D.;
- ARTHUR J. LEWIS, M.D.;
- J. MURRAY STEELE, M.D.;
- Dorothy Andrews, B.A.,
Sympathectomy involves division of adrenergic, cholinergic and sensory fibers which elaborate adrenergic substances during the process of regulating visceral function
G. SURGICAL SYMPATHECTOMY AND ADRENERGIC FUNCTIONPharmacol Rev March 1966 18:611-618;