The literature contains reports of remission with sympathectomy, but careful case selection is imperative before this procedure is performed. Sympathectomy should be considered only for those whose erythromelalgia improves with blocks. Conversely, if a sympathetic block causes worsening of a person's erythromelalgia, treatment should be discontinued. Sympathectomy should not be considered for such persons because of the risk of permanent worsening of erythromelalgia symptoms.
Jay S. Cohen MD,
medicationsense.com/articles/2010/erythromelalgia0510.pdf