"Sympathectomy is a technique about which we have limited knowledge, applied to disorders about which we have little understanding." Associate Professor Robert Boas, Faculty of Pain Medicine of the Australasian College of Anaesthetists and the Royal College of Anaesthetists, The Journal of Pain, Vol 1, No 4 (Winter), 2000: pp 258-260
Monday, September 20, 2010
surgical sympathectomy produces hypersensitivity of the vessels.
Scand J Work En viron Health 13 (1987) 3 1 3 - 3 1 6
Depression of Endothelial Nitric Oxide Synthase
but Increased Expression of Endothelin-1 Immunoreactivity in Rat Thoracic Aortic Endothelium Associated With Long-term, but Not Short-term, Sympathectomy.
Aliev, Gjumrakch; Ralevic, Vera; Burnstock, Geoffrey
Original Contribution
Circulation Research. 79(2):317-323, August 1996.Aliev, Gjumrakch; Ralevic, Vera; Burnstock, Geoffrey
Denervation supersensitivity in the denervated heart
The guanethidine sympathectomy in 4- and 8-week old white rats increased cardiac sensitivity to acetylcholine. An increase of sensitivity to adrenaline was observed in 8 to 20 weeks of postnatal period. The significance of the changes of extracardiac effects and the cardiac sensitivity to acetylcholine and adrenaline for its chronotropic control in sympathectomized 10-14 week old rats is discussed.
http://www.ncbi.nlm.nih.gov/pubmed/3569584
http://www.ncbi.nlm.nih.gov/pubmed/3569584