We have observed spontaneous vasospasm in the hands on emotional disturbances within ten days after sympathectomy, but no clinical evidence of this in the feet. I believe that sensitization of the denervated smooth muscle in the digital arterioles to adrenine is a better explanation of this phenomenon than local sensitivity to cold (Lewis, 1930), incomplete sympathectomy (Adson, and Leriche and Fontaine, 1933), or the common argument that Raynaud's disease is moresevere in the hands than in the feet.
PROCEEDINGS OF THE TWENTY-SEVENTH ANNUAL MEETING OF THE
AMERICAN SOCIETY FOR CLINICAL INVESTIGATION
HELD IN ATLANTIC CITY, N. J., MAY 6, 1935