H-NOREPINEPHRINE UPTAKE
Portal veins were incubated for 1 hour with 3H-NE 1,3, and 5 days after chemical sympathectomy with 6-OHDA (Fig. 3). Preparations treated with cocaine (10~5 M) were exposed to this drug 15 minutes before 3H-NE incubation and maintained in a cocaine-containing solution throughout the entire incubation period. One day after 6-OHDA treatment, NE uptake was reduced to approximately 21 %
of control; at 3 days it was 33% of controls and 5 days after 6-OHDA it was approximately 39% of controls. The decrease in NE uptake caused by 6-OHDA treatment was comparable to that caused by cocaine.
SUPERSENSITIVITY TO NE AFTER ADRENERGIC DENERVATION
CATECHOLAMINE DEPLETION AFTER CHEMICAL SYMPATHECTOMY
1977;41;198-206 Circ. Res.
Trophic influence of the sympathetic nervous system on the rat portal vein