Sunday, August 9, 2009

Reduced Heart Rate Variability associated with incresed mortality

These results support an association between CAN (cardiovascular autonomic neuropathy) and increased risk of mortality. The stronger association observed in studies defining CAN by the presence of two or more abnormalities may be due to more severe autonomic dysfunction in these subjects or a higher frequency of other comorbid complications that contributed to their higher mortality risk. Future studies should evaluate whether early identification of subjects with CAN can lead to a reduction in mortality.
  1. Raelene E. Maser, PHD1,
  2. Braxton D. Mitchell, PHD2,
  3. Aaron I. Vinik, MD, PHD3 and
  4. Roy Freeman, MD4