Wednesday, September 24, 2008

Sympathectomy induces novel purinergic sensitivity in sciatic afferents

Acta Pharmacol Sin. 2000 Nov;21(11):1002-4.

Chen Y, Zhang YH, Bie BH, Zhao ZQ. Shanghai Institute of Physiology, Chinese Academy of Sciences, Shanghai 200031, China

Twenty eight percent of the spontaneously active afferent fibers from sciatic nerves in the sympathectomized rats responded to ATP, either with an increase or with a decrease in spontaneous firing. However, none of the fibers from the sciatic nerves in the intact rats was activated by ATP. CONCLUSION: Sympathectomy induces novel purinergic sensitivity in A afferents from sciatic nerve.
http://www.ncbi.nlm.nih.gov/pubmed/11501053

Classification of the surgery by the International Society of Sympathetic Surgeons

Here are the basics of our new classifications:
ESB2 (clamp upper end of T2 only): 2.5%, (in Europe 15%)
Facial blushing, Craniofacial sweating, Some psychic disorders, Rosacea, Vibration disorder (?), Parkinsonism (?)...
ESB3: 2.5%, (in Europe 50%)
Hyperhidrosis Palmaris with Craniofacial sweating, blushing, or any other craniofacial sympathetic disorders
ESB4: 95%, (in Europe 20%)
Hyperhidrosis Palmaris with or without axillary hyperhidrosis (Bromidrosis)
Unilateral ESB: (in Europe 15%)
Social phobia, schizophrenia, sleep disorders, addiction, cardiac arrhythmias

Conclusion: The patients are individuals with individual symptom complexes. There does not seem to exist any clear-cut Hyperhidrosis disease, Blushing disease, nor necessarily any social phobia disease, or schizophrenia disease. All these states are symptom complexes of multiple origin, and should be treated individually along the proposed guidelines.

http://www.hyperhidrosis.com/symposium.htm

Mia: If you are not comfortable undergoing the same surgery that treats heart patients and psychiatric disorders (among many), then you are advised to seek other alternative treatment for your condition.