Sunday, August 31, 2008

Abnormal pain following nerve sprouting

Collectively, our findings indicate that as a result of autonomic sprouting due to CCI of the MN, remaining intact nociceptive fibres may potentially develop sensitivity to sympathetic and parasympathetic stimulation, which may have a role in the generation of abnormal pain following nerve injury.

Received 22 October 2004, revised 17 February 2005, accepted 23 February 2005

C. Grelik 1 , G. J. Bennett 3,4,5 and A. Ribeiro-da-Silva 1,2,5
1 Department of Pharmacology & Therapeutics, McGill University, 3655 Prom. Sir-William-Osler, Montreal, Quebec, Canada H3G 1Y6
2 Department of Anatomy and Cell Biology,
3 Department of Anesthesia,
4 Faculty of Dentistry, and
5 McGill Centre for Research on Pain, McGill University, Montreal, Quebec, Canada