In rodents, chemical sympathectomy attenuates primary
splenic antibody responses to systemic immunisation and lymph-node antibody responses to footpad challenge, suppresses cytotoxic T-cell responses to allogeneic cells, and reduces delayed-type hypersensitivity reactions; it is also associated with an enhancement of in-vivo lymphoproliferation in some lymph nodes and an increase in natural killer (NK) cell activity.'[ 11, 12] Chemical sympathectomy also increases the severity of experimental allergic encephalomyelitis[ 13] and adjuvant-induced arthritis in susceptible strains of rats. [ 14]
Psychoneuroimmunology: Interactions between the nervous system and the immune system.
Source: Lancet, 1/14/95, Vol. 345 Issue 8942, p99, 5p,
Author(s): Ader, Robert; Cohen, Nicholas