Sunday, April 13, 2008

sympathectomy impairing adrenergic transmission

The chronic bilateral cervical superior sympathectomy could provoke norepinephrine depletion in the small granular vesicles of the sympathetic terminals, impairing adrenergic transmission; this would then eliminate the constrictor sympathetic effect13. Our study is in agreement with published data where pharmacological or anatomical exclusion of the sympathetic activity prevented vasospasm24.

Antônio Tadeu de Souza FaleirosI; Francisco Humberto de Abreu MaffeiII; Luiz Antonio de Lima ResendeIII

IServices of Neurosurgery, Botucatu School of Medicine, São Paulo State University (UNESP), Botucatu, SP, Brazil
IIVascular Surgery, Botucatu School of Medicine, São Paulo State University (UNESP), Botucatu, SP, Brazil
IIINeurology, Botucatu School of Medicine, São Paulo State University (UNESP), Botucatu, SP, Brazil