Saturday, April 19, 2008

Marked depletion of cardiac catecholamines (80 to 90%) following denervation

Can. J. Physiol. Pharmacol. 48(3): 182–184 (1970) | doi:10.1139/y70-031 | © 1970 NRC Canada

Effect of cardiac sympathectomy, reserpine, and environmental temperatures on the catecholamine levels in the chicken heart


Y. C. Lin, P. D. Sturkie, and J. Tummons


Abstract: Cardiac catecholamine levels were spectrofluorometrically determined in adult male chickens following two treatments: (1) denervation of the cardioaccelerator nerves or (2) reserpine administration after acclimatization of the birds to low, intermediate, or high ambient temperatures. Marked depletion of cardiac catecholamines (80 to 90%) was found 2 weeks after denervation and 24 h after injection of reserpine. Acclimatization did not alter the response to reserpine.