Monday, March 24, 2008

Sympathectomy Enhances Calcitonin Gene-Related Peptide and Substance-P Expression

Ethridge, Richard T.; Supowit, Scott C.; Zhao, Huawei; DiPette, Donald J.
Institution
University of Texas Medical Branch, Galveston, TX.

Permanent Sympathectomy Enhances Calcitonin Gene-Related Peptide and Substance-P Expression In Dorsal Root Ganglion Neurons.

Hypertension. 32(3):604, September 1998.



Substance P: In the central nervous system, substance P has been associated in the regulation of mood disorders, anxiety, stress, reinforcement, neurogenesis, respiratory rhythm, neurotoxicity, nausea / emesis and pain.
It also has effects as a potent vasodilator. This is caused by the release of nitric oxide from the endothelium. Its release can cause hypotension.

http://en.wikipedia.org/wiki/Substance_P