Monday, March 24, 2008

SUPRESSION OF BARORECEPTOR FUNCTION OF THE HEART

Dohi, Shuji MD; Tsuchida, Hideaki MD; Mayumi, Takehisa MD
Institution
Institute of Clinical Medicine, University of Tsukuba, Sakuramura, Ibaraki, Japan, and the Department of Anesthesiology, Sapporo Medical College and Hospital, Sapporo, Hokkaido, Japan.
Title
Baroreflex Control of Heart Rate during Cardiac Sympathectomy by Epidural Anesthesia in Lightly Anesthetized Humans.[Article]
Source
Anesthesia & Analgesia. 62(9):815-820, September 1983.
To evaluate the effects of acute sympathetic denervation on the baroreflex control of heart rate, baroreflex sensitivities were compared in lightly anesthetized humans who had either cervical (N = 20) or lumbar epidural anesthesia (N = 18). The results suggest that cardiac sympathectomy induced by epidural anesthesia can suppress partially baroreceptor function by interrupting sympathetic efferent fibers innervating the heart during high levels of epidural anesthesia, but that lumbar sympathectomy during epidural anesthesia is unlikely to affect baroreceptor activity.