"Due to side effects, oral medications are not recommended as a long-term solution. Similarly, surgical options, although heavily advertised, are reserved for only certain severe cases of hyperhidrosis that have not responded to any of the other treatment options. Before considering surgical treatment, physicians and their patients must fully consider and discuss the very real risks of permanent damage and severe side effects."
http://www.sweathelp.org/English/PFF_Treatment_Overview.asp