These results indicate that
alterations in the relative abundance of TH mRNA mediate changes in TH activity induced by
chronic stress or sympathectomy, and that these changes require an intact sympathetic input.
Molecular adaptations in catecholamine biosynthesis induced
by cold stress and sympathectomy
M.K. Stachowiak 1, S.J. Fluharty 2, E.M. Stricker 2, M.J. Zigmond 3, B.B. Kaplan, Ph.D. 1 *
1
Department of Psychiatry, Center for Neuroscience, University of Pittsburgh, Pittsburgh,
Pennsylvania
2
Department of Psychology, Center for Neuroscience, University of Pittsburgh, Pittsburgh,
Pennsylvania
3
Department of Biological Sciences, Center for Neuroscience, University of Pittsburgh, Pittsburgh,
Pennsylvania
Epinephrine Produces a -Adrenergic
Receptor-Mediated Mechanical Hyperalgesia and
In Vitro Sensitization of Rat Nociceptors
Sachia G. Khasar, Gordon McCarter, and Jon D. Levine
Departments of Medicine and Oral and Maxillofacial Surgery, Division of
Neuroscience and Biomedical Sciences Program, National Institutes of Health
Pain Center (UCSF), University of California, San Francisco, California
94143-0440